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ZBTB2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501564683
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Catalog No. Quantity
50-156-4683 10 μL
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Catalog No. 50-156-4683 Supplier Bethyl Laboratories, Inc Supplier No. A303261AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

ZBTB2 is a member of the POK (POZ domain Krüppel-like zinc finger) family and plays an important role in cell cycle regulation. It is a transcription factor and a potent repressor of the ARF-HDM2-p53-p21 pathway. ZBTB2 represses the transcription of the p21, p53 and ARF genes and activates HDM2 gene. ZBTB2 and Sp1 compete with each other in binding to the GC-box 5/6 elements and the two p53 binding elements. ZBTB2 directly interacted with p53 via its zinc fingers, inhibiting p53 binding and repressing transcription activation by p53.

Specifications

Antigen ZBTB2
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ZBTB2
Gene Accession No. Q8N680
Gene Alias Zinc finger and BTB domain-containing protein 2; ZNF437; KIAA1483; ZBTB2
Gene Symbols ZBTB2
Host Species Rabbit
Immunogen Between 50 and 100
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57621
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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