ZBTB5 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS13581R

Catalog No. 50-198-2996

Description

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.

Specifications

• Antigen: ZBTB5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZBTB5
• Gene Alias: 5930421I10; 9430083K24Rik; AI646847; expressed in brain and neural tube; KIAA0354; mKIAA0354; RP11-397D12.5; Transcription factor ZNF-POZ; Zbtb5; zinc finger and BTB domain containing 5; Zinc finger and BTB domain-containing protein 5
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9925
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: O15062
• Gene Symbols: ZBTB5
• Immunogen: KLH conjugated synthetic peptide derived from human ZBTB5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG