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Invitrogen™ ZC3H12B Polyclonal Antibody
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Catalog No. PIPA551464
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100 μL
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PIPA551464 100 μL
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Catalog No. PIPA551464 Supplier Invitrogen™ Supplier No. PA551464
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GRALVMTRMD SISDSRLYES NPVRQRRPPL CREQHASWDP LPCTTDSYGY HSYPLSNSLM QPCYEPVMVR SVPEKMEQLW RNPWVGMCND SREHMIPEHQ YQTYKNLCN Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZC3H12B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZC3H12B
Gene Accession No. Q5HYM0
Gene Alias A130028J20Rik; CXorf32; Gm373; MCP-induced protein 2; MCPIP2; Probable ribonuclease ZC3H12B; RGD1560891; RP3-475B7.1; Zc3h12b; Zinc finger CCCH domain-containing protein 12B; zinc finger CCCH-type containing 12B
Gene Symbols ZC3H12B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZC3H12B. Recombinant protein control fragment (Product #RP-91996).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 340554
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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