Invitrogen™ ZC3H12D Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520929

Catalog No. PIPA520929

Description

A suggested positive control is THP-1 cell lysate. PA5-20929 can be used with blocking peptide PEP-1043.

ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.

Specifications

• Antigen: ZC3H12D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZC3H12D
• Gene Alias: C6orf95; D730019B10Rik; dJ281H8.1; MCP-induced protein 4; MCPIP4; p34; probable ribonuclease ZC3H12D; RP1-281H8.5; Tfl; Transformed follicular lymphoma; transformed follicular lymphoma homolog; tumor suppressor TFL; zc3h12d; Zinc finger CCCH domain-containing protein 12D; zinc finger CCCH type containing 12D; zinc finger CCCH-type containing 12D
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 340152
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: A2A288
• Gene Symbols: ZC3H12D
• Immunogen: A 17 amino acid peptide near the carboxy terminus of human ZC3H12D.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG