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Invitrogen™ ZC3H12D Polyclonal Antibody
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Catalog No. PIPA5110590
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100 μL
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PIPA5110590 100 μL
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Catalog No. PIPA5110590 Supplier Invitrogen™ Supplier No. PA5110590
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QHVLAELERQ AVLVYTPSRK VHGKRLVCYD DRYIVKVAYE QDGVIVSNDN YRDLQSENPE WKWFIEQRLL MFSFVNDRFM P.

ZC3H12D, also known as MCPIP4, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. ZC3H12D is highly expressed in spleen, intestine, and colon. Similar to ZC3H12A and ZC3H12C, ZC3H12D expression in murine macrophages is also increased after treatment with lipopolysaccharide (LPS), although not to the same level as ZC3H12A. This pattern of expression was not duplicated in human-derived macrophages, suggesting it also may play a different role in host immunity and inflammatory response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZC3H12D
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ZC3H12D
Gene Accession No. A2A288, Q8BIY3
Gene Alias C6orf95; D730019B10Rik; dJ281H8.1; MCP-induced protein 4; MCPIP4; p34; probable ribonuclease ZC3H12D; RP1-281H8.5; Tfl; Transformed follicular lymphoma; transformed follicular lymphoma homolog; tumor suppressor TFL; zc3h12d; Zinc finger CCCH domain-containing protein 12D; zinc finger CCCH type containing 12D; zinc finger CCCH-type containing 12D
Gene Symbols ZC3H12D
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 150-230 of human ZC3H12D (NP_997243.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 237256, 308266, 340152
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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