ZC3H8 Monoclonal Antibody (OTI3G10), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-2105	100 μL

Catalog No. 50-168-2105 Supplier OriGene Supplier No. TA808400

Description

Mouse Monoclonal Antibody

ZC3H8 acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5′-AGGTCTC-3′ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Specifications

• Antigen: ZC3H8
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI3G10
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: ZC3H8
• Gene Accession No.: Q8N5P1
• Gene Alias: Fliz1, ZC3HDC8
• Gene Symbols: ZC3H8
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human ZC3H8 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 84524
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1