ZC3H8 Mouse anti-Human, Clone: OTI5B12, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808242

Catalog No. 50-166-8718

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

ZC3H8 acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5′-AGGTCTC-3′ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Specifications

• Antigen: ZC3H8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ZC3H8
• Gene Alias: Fliz1, ZC3HDC8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84524
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI5B12
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8N5P1
• Gene Symbols: ZC3H8
• Immunogen: Full length human recombit protein of human ZC3H8 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1