ZC3H8 Mouse anti-Human, Clone: OTI5B12, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-8718	100 μg

Catalog No. 50-166-8718 Supplier OriGene Supplier No. CF808242

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

ZC3H8 acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5′-AGGTCTC-3′ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Specifications

• Antigen: ZC3H8
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5B12
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: ZC3H8
• Gene Accession No.: Q8N5P1
• Gene Alias: Fliz1, ZC3HDC8
• Gene Symbols: ZC3H8
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human ZC3H8 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 84524
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1