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Invitrogen™ ZC3HAV1 Polyclonal Antibody
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Catalog No. PIPA5111479
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100 μL
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PIPA5111479 100 μL
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Catalog No. PIPA5111479 Supplier Invitrogen™ Supplier No. PA5111479
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RFVVLETGGE AGITRSVVAT TRARVCRRKY CQRPCDNLHL CKLNLLGRCN YSQSERNLCK YSHEVLSEEN FKVLKNHELS GLNK Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 87%.

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZC3HAV1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Zc3hav1
Gene Accession No. Q7Z2W4
Gene Alias 1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik; ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; CCCH-type zinc finger antiviral protein (Zap); D6Bwg1452e; FLB6421; Inactive Poly [ADP-ribose] polymerase 13; PARP13; PRO1677; rZAP; ZAP; ZC3H2; Zc3hav1; ZC3HDC2; zinc finger antiviral protein; Zinc finger CCCH domain-containing protein 2; zinc finger CCCH type, antiviral 1; zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type containing, antiviral 1; zinc finger CCCH-type, antiviral 1
Gene Symbols Zc3hav1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human ZC3HAV1. Recombinant protein control fragment (Product #RP-106915).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56829
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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