ZCCHC17 Monoclonal Antibody (OTI1F11), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809515

Catalog No. 50-168-2847

Description

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson′s disease, Gaucher disease and Usher syndrome.

Specifications

• Antigen: ZCCHC17
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9NP64
• Gene Symbols: ZCCHC17
• Immunogen: Full length human recombit protein of human ZCCHC17 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI1F11
• Conjugate: Unconjugated
• Gene: ZCCHC17
• Gene Alias: HSPC251, PS1D, pNO40
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51538
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid