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ZDHHC16 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA558965
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PIPA558965 100 μL
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Catalog No. PIPA558965 Supplier Thermo Scientific Supplier No. PA558965

Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLISRGETSI ERHINKKERR RLQAKGRVFR NPYNYGCLDN WKVFLGVDTG RHWLTRVLLP SSHLPHGNGM SWEPPPWVTA Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one DHHC-type zinc finger. Existing as multiple alternatively spliced isoforms, ZDHHC16 interacts with c-Abl and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Via its association with c-Abl, ZDHHC16 may be involved in the regulation of apoptosis. The gene encoding ZDHHC16 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZDHHC16
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZDHHC16
Gene Accession No. Q969W1
Gene Alias 1500015N03Rik; Abl-philin 2; ablphilin-2; Aph2; DHHC-16; membrane-associated DHHC16 zinc finger protein; Palmitoyltransferase ZDHHC16; probable palmitoyltransferase ZDHHC16; UNQ2570/PRO6258; Zdhhc16; Zinc finger DHHC domain-containing protein 16; zinc finger DHHC-type containing 16; zinc finger, DHHC domain containing 16; zinc finger, DHHC-type containing 16
Gene Symbols ZDHHC16
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZDHHC16
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84287
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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