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Invitrogen™ ZDHHC18 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA575752
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.
Specifications
ZDHHC18 | |
Polyclonal | |
Unconjugated | |
ZDHHC18 | |
DHHC18; DHHC-18; membrane-associated DHHC18 zinc finger protein; palmitoyltransferase ZDHHC18; Zdhhc18; Zinc finger DHHC domain-containing protein 18; zinc finger DHHC-type containing 18; zinc finger, DHHC domain containing 18; zinc finger, DHHC-type containing 18 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
84243 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9NUE0 | |
ZDHHC18 | |
Synthetic peptide corresponding to residues in Human ZDHHC18. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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