Invitrogen™ ZDHHC18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116614

Catalog No. PIPA5116614

Description

Positive Samples: Raji, HeLa, Mouse brain, Rat brain Immunogen sequence: YLVASNLTTN EDIKGSWSSK RGGEASVNPY SHKSIITNCC AVLCGPLPPS LIDRRGFVQS DTVLPSPIRS DEPACRAKPD ASMVGGHP.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.

Specifications

• Antigen: ZDHHC18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZDHHC18
• Gene Alias: DHHC18; DHHC-18; membrane-associated DHHC18 zinc finger protein; palmitoyltransferase ZDHHC18; Zdhhc18; Zinc finger DHHC domain-containing protein 18; zinc finger DHHC-type containing 18; zinc finger, DHHC domain containing 18; zinc finger, DHHC-type containing 18
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 362613, 503610, 84243
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.99 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q2TGJ1, Q5Y5T2, Q9NUE0
• Gene Symbols: ZDHHC18
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 301-388 of human ZDHHC18 (NP_1156591).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG