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ZEB1/2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985960
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50-198-5960 100 μL
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Catalog No. 50-198-5960 Supplier Bioss Supplier No. BS4187R
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Description

Rabbit Polyclonal Antibody

ZEB1 (Zinc finger E-box-binding homeobox 1) acts as a transcriptional repressor. It inhibits interleukin-2 (IL-2) gene expression. ZEB1 enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and depending on the cell type. It represses E-cadherin promoters and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. ZEB1 also represses BCL6 transcription in the presence of the corepressor CTBP1. It postively regulates neuronal differentiation and represses RCOR1 transcription activation during neurogenesis. Mutations in the gene can result in corneal dystrophy, posterior polymorphous and corneal dystrophy, Fuchs endothelial 6.

Specifications

Antigen ZEB1/2
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ZEB1
Gene Accession No. P37275
Gene Alias [delta]EF1; 3110032K11Rik; AREB6; BOS_12951; BZP; Delta EF1; delta-crystallin enhancer binding factor 1; DELTAEF1; DELTA-EF1; FECD6; MEB1; MGC133261; Negative regulator of IL2; Nil2; NIL2A; NIL-2A; NIL-2-A; NIL-2-A zinc finger protein; OTTHUMP00000019405; posterior polymorphous corneal dystrophy 3; PPCD3; RP11-472N13.4; Tcf18; Tcf8; TCF-8; Transcription factor 8; transcription factor 8 (represses interleukin 2 expression); Tw; twirler; ZEB; Zeb1; Zfhep; Zfhx1a; Zfx1a; Zfx1ha; zinc finger E-box binding homeobox 1; Zinc finger E-box-binding homeobox 1; Zinc finger homeobox protein 1a; Zinc finger homeodomain enhancer-binding protein
Gene Symbols ZEB1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ZEB1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6935
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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