Invitrogen™ ZFP95 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551857

Catalog No. PIPA551857

Description

Immunogen sequence: EHHPESGEEA VAVIENIQRE LEERRQQIVA CPDVLPRKMA TPGAVQESCS PHPLTVDTQP EQAPQKPRLL EENALPVLQV PSLPLKDSQE LTASLLSTGS QKLVKIEEVA DVAVSFILEE WGHLDQSQKS LYRDDRKENY GSITS Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 77%.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. A member of the Krüppel C2H2-type zinc-finger protein family, ZKSCAN5, also known as ZFP95, is a 839 amino acid protein containing thirteen C2H2-type zinc fingers, one KRAB A domain and one SCAN box domain. ZKSCAN5 is located in the nucleus and is highly expressed in testis with lower levels of expression in liver, kidney, brain, striated muscle, lung and heart. Many KRAB A box-containing proteins have been shown to function as transcription repressors, suggesting a possible function of ZKSCAN5. As a result of alternative splicing, three transcripts of ZKSCAN5 exist, however one of those transcripts is specific to testis. The mouse homolog of ZKSCAN5 is differentially expressed in spermatogenesis.

Specifications

• Antigen: ZFP95
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZKSCAN5
• Gene Alias: AI132486; AI326970; hKraba1; KIAA1015; ZFP95; ZFP-95; Zinc finger protein 95; zinc finger protein 95 homolog; zinc finger protein homologous to Zfp95 in mouse; zinc finger protein with KRAB and SCAN domains 5; zinc finger with KRAB and SCAN domains 5; Zkscan5; ZNF914; ZSCAN37
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23660
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y2L8
• Gene Symbols: ZKSCAN5
• Immunogen: Recombinant protein corresponding to Human ZFP95. Recombinant protein control fragment (Product #RP-99734).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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