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Invitrogen™ ZFPM1 Polyclonal Antibody
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Catalog No. PIPA5120619
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100 μL
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PIPA5120619 100 μL
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Catalog No. PIPA5120619 Supplier Invitrogen™ Supplier No. PA5120619
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, Mouse liver, Mouse brain, Rat liver. Immunogen sequence: MSRRKQSNPR QIKRSLGDME AREEVQLVGA SHMEQKATAP EAPSPPSADV NSPPPLPPPT SPGGPKELEG QEPEPRPTEE EPGSPWSGPD ELEPVVQDGQ RRIRARLSLA TGLSWGPFHG SVQTRASSPR QAEPSPALTL LLVDEACWLR TLPQALTEAE ANTEIHRKDD ALWCRVTKPV PAGGLLSVLL TAEPHSTPGH PVKKEPAEPT CPAPAHDLQL LPQQAGMASI.

ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZFPM1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene ZFPM1
Gene Accession No. O35615, Q8IX07
Gene Alias FOG; Fog1; FOG-1; friend of GATA 1; friend of GATA protein 1; Friend of GATA-1; ZC2HC11A; ZFN89A; Zfpm1; Zinc finger protein 89A; Zinc finger protein multitype 1; Zinc finger protein ZFPM1; zinc finger protein, FOG family member 1; zinc finger protein, multitype 1; ZNF408; ZNF89A
Gene Symbols ZFPM1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ZFPM1 (NP_722520.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 161882, 22761, 691504
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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