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Invitrogen™ ZFYVE19 Polyclonal Antibody
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Catalog No. PIPA5101963
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100 μL
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PIPA5101963 100 μL
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Catalog No. PIPA5101963 Supplier Invitrogen™ Supplier No. PA5101963
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ZFYVE19.

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZFYVE19
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ZFYVE19
Gene Accession No. Q96K21, Q9DAZ9
Gene Alias 1500041L05Rik; abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; MPFYVE; Zfyve19; Zinc finger FYVE domain-containing protein 19; zinc finger FYVE-type containing 19; zinc finger, FYVE domain containing 19
Gene Symbols ZFYVE19
Host Species Rabbit
Immunogen A synthesized peptide derived from human ZFYVE19(Accession Q96K21), corresponding to amino acid residues E315-Q365.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 72008, 84936
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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