ZFYVE19 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301807AT

Catalog No. 50-155-9764

Description

The recommended shelf life for this product is 1 year from date of receipt.

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission

Specifications

• Antigen: ZFYVE19
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZFYVE19
• Gene Alias: MPFYVE, MLL partner containing FYVE domain, zinc finger FYVE domain-containing protein 19
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84936
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q96K21
• Gene Symbols: ZFYVE19
• Immunogen: Between 375 and 425
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG