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ZFYVE19 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734007 Shop All Proteintech Group Inc Products
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150 μL
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50-173-4007 150 μL
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Catalog No. 50-173-4007 Supplier Proteintech Group Inc Supplier No. 231631AP150UL
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Description

Rabbit Polyclonal Antibody

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission

Specifications

Antigen ZFYVE19
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ZFYVE19
Gene Accession No. Q96K21
Gene Alias MPFYVE, ZFYVE19
Gene Symbols ZFYVE19
Host Species Rabbit
Immunogen ZFYVE19 Fusion Protein Ag19593
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84936
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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