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  6. ZFYVE21 Monoclonal Antibody (OTI4A2), TrueMAB™, OriGene 

ZFYVE21 Monoclonal Antibody (OTI4A2), TrueMAB™, OriGene
SDP

Catalog No. 501676067
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100 μL
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Catalog No. Quantity
50-167-6067 100 μL
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Catalog No. 50-167-6067 Supplier OriGene Supplier No. TA505622
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Description

Mouse Monoclonal Antibody

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.

Specifications

Antigen ZFYVE21
Applications Western Blot
Classification Monoclonal
Clone OTI4A2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ZFYVE21
Gene Accession No. Q9BQ24
Gene Alias HCVP7TP1, ZF21
Gene Symbols ZFYVE21
Host Species Mouse
Immunogen Full length human recombit protein of human ZFYVE21 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79038
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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