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ZFYVE21 Mouse anti-Human, Clone: OTI4A2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF505622

Encompass_Preferred

Catalog No. 50-166-3784


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
Specifications

Specifications

ZFYVE21
Monoclonal
Unconjugated
ZFYVE21
HCVP7TP1, ZF21
Mouse
Affinity Chromatography
RUO
79038
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI4A2
PBS with 8% trehalose and no preservative; pH 7.3
Q9BQ24
ZFYVE21
Full length human recombit protein of human ZFYVE21 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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