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Invitrogen™ ZFYVE21 Polyclonal Antibody
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Catalog No. PIPA563165
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100 μL
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PIPA563165 100 μL
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Catalog No. PIPA563165 Supplier Invitrogen™ Supplier No. PA563165
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SGATFLVTFG NSEKPETMTC RLSNNQRYLF LDGDSHYEIE IVHISTVQIL TEGFPPGGGN ARATGMFLQY TVPG Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.

ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZFYVE21
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZFYVE21
Gene Accession No. Q9BQ24
Gene Alias 1110013H04Rik; AW558780; C85416; FYVE domain containing 21; HCV p7-transactivated protein 1; HCVP7TP1; ZF21; Zfyve21; Zinc finger FYVE domain-containing protein 21; zinc finger FYVE-type containing 21; zinc finger, FYVE domain containing 21
Gene Symbols ZFYVE21
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZFYVE21. Recombinant protein control fragment (Product #RP-98355).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79038
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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