Invitrogen™ ZGLP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562064

Catalog No. PIPA562064

Description

Immunogen sequence: LLDRDSKDTQ TRISQKGRRL QPPGTPSAPP QRRPRKQLNP CRGTERVDPG FEGVTLKFQI KPDSSLQIIP TYSLPCSSRS QE Highest antigen sequence identity to the following orthologs: Mouse - 50%, Rat - 50%.

Glucagon is initially synthesized as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.

Specifications

• Antigen: ZGLP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZGLP1
• Gene Alias: GATA like protein 1; GATA like protein-1; GATA zinc finger domain containing 3; GATAD3; GATA-like 1; GATA-like protein 1; GATA-type zinc finger protein 1; Glp1; GLP-1; ZGLP1; zinc finger, GATA-like protein 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100125288
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P0C6A0
• Gene Symbols: ZGLP1
• Immunogen: Recombinant protein corresponding to Human ZGLP1. Recombinant protein control fragment (Product #RP-99247).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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