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Invitrogen™ ZGPAT Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5113754
Description
Immunogen sequence: AGRHSVASAQ LQEKLAGAQR QLGQLRAQEA GLQQEQRKAD THKKMTEF For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 93%; Sheep: 93%.
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt].
Specifications
ZGPAT | |
Polyclonal | |
Unconjugated | |
ZGPAT | |
1500006I01Rik; BC021513; G patch domain-containing protein 6; GPATC6; GPATCH6; KIAA1847; RGD1310801; ZC3H9; ZC3HDC9; ZGPAT; Zinc finger and G patch domain-containing protein; zinc finger CCCH domain-containing protein 9; zinc finger CCCH-type and G-patch domain containing; zinc finger CCCH-type with G patch domain; zinc finger CCCH-type with G patch domain-containing protein; zinc finger, CCCH-type with G patch domain; zinc finger, CCCH-type with G patch domain isoform c; zinc finger, CCCH-type with G-patch domain; ZIP | |
Rabbit | |
Affinity Chromatography | |
RUO | |
84619 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
Q8N5A5 | |
ZGPAT | |
Synthetic peptide directed towards the C terminal region of human ZGPAT. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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