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ZGPAT Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984288
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100 μL
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50-198-4288 100 μL
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Catalog No. 50-198-4288 Supplier Bioss Supplier No. BS19161R
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Description

Rabbit Polyclonal Antibody

Transcription repressor that specifically binds the 5′-GGAG[GA]A[GA]A-3′ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Specifications

Antigen ZGPAT
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ZGPAT
Gene Accession No. Q8N5A5
Gene Alias 1500006I01Rik; BC021513; BOS_13367; G patch domain-containing protein 6; GPATC6; GPATCH6; KIAA1847; RGD1310801; ZC3H9; ZC3HDC9; Zgpat; Zinc finger and G patch domain-containing protein; Zinc finger CCCH domain-containing protein 9; zinc finger CCCH-type and G-patch domain containing; zinc finger CCCH-type with G patch domain; Zinc finger CCCH-type with G patch domain-containing protein; zinc finger, CCCH-type with G patch domain; zinc finger, CCCH-type with G-patch domain; ZIP
Gene Symbols ZGPAT
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ZGPAT.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84619
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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