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Invitrogen™ ZHX2 Monoclonal Antibody (OTI2E11)
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Catalog No. PIMA527337
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100 μL
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PIMA527337 100 μL
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Catalog No. PIMA527337 Supplier Invitrogen™ Supplier No. MA527337
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Description

Mouse Monoclonal Antibody

ZHX2 Monoclonal Antibody for Western Blot, IHC (P)

Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZHX2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2E11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ZHX2
Gene Accession No. Q8C0C0, Q9Y6X8
Gene Alias AFP regulator 1; AFR1; Afr-1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; KIAA0854; LOW QUALITY PROTEIN: zinc fingers and homeoboxes protein 2; mKIAA0854; Raf; Regulator of AFP; transcription factor ZHX2; Zhx2; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; zinc fingers and homeoboxes protein 2; zinc-fingers and homeoboxes 2
Gene Symbols ZHX2
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 595-837 of ZHX2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22882, 387609
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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