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Invitrogen™ ZHX2 Polyclonal Antibody
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Catalog No. PIPA5120626
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100 μL
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PIPA5120626 100 μL
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Catalog No. PIPA5120626 Supplier Invitrogen™ Supplier No. PA5120626
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Description

Rabbit Polyclonal Antibody

Positive test controls include: U-251MG, 293T, Raji, LO2, Mouse brain. Immunogen sequence: SDHRYRCQRG IVHITSESLA KDQLAIAASR HGRTYHAYPD FAPQKFKEKT QGQVKILEDS FLKSSFPTQA ELDRLRVETK LSRREIDSWF SERRKLRDSM EQAVLDSMGS GKKGQDVGAP NGALSRLDQL SGAQLTSSLP SPSPAIAKSQ EQVHLLRSTF ARTQWPTPQE YDQLAAKTGL VRTEIVRWFK ENRCLLKTGT VKWMEQYQHQ PMADDHGYDA VARKATKPMA ESPKNGGDVV PQYYKDPKKL CEEDLEKLVT RVKVGSEPAK DCLPAKPSEA TSDRSEGSSR DGQGSDENEE SSVVDYVEVT VGEEDAISDR SDSWSQAAAE GVSELAESDS DCVPAEAGQA.

Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZHX2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ZHX2
Gene Accession No. Q80VX4, Q8C0C0, Q9Y6X8
Gene Alias AFP regulator 1; AFR1; Afr-1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; KIAA0854; LOW QUALITY PROTEIN: zinc fingers and homeoboxes protein 2; mKIAA0854; Raf; Regulator of AFP; transcription factor ZHX2; Zhx2; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; zinc fingers and homeoboxes protein 2; zinc-fingers and homeoboxes 2
Gene Symbols ZHX2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 488-837 of human ZHX2 (NP_055758.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22882, 314988, 387609
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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