Invitrogen™ Zika Virus Envelope Recombinant Rabbit Monoclonal Antibody (HL1699)

Catalog No.	Quantity
PIMA547144	100 μL

Catalog No. PIMA547144

Supplier: Invitrogen™ MA547144

Description

Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. and Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.

Specifications

• Antigen: Zika Virus Envelope
• Applications: Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: HL1699
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene Alias: Zika Envelope
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to Zika virus Envelope protein.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG