Invitrogen™ Zika Virus prM (strain H/PF/2013) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143433

Catalog No. PIPA5143433

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial. Positive control: Zika virus(PRVABC59)-infected Vero, Zika virus prM-infected C6/36.

Zika virus has biological similarities to other flaviviruses, such as West Nile virus, Japanese encephalitis virus (JEV) and dengue virus ZIKV has an approximately 11 kb positive-stranded RNA genome, with untranslated regions flanking the 5' and 3' ends of its open reading frame The genome is translated into structural proteins [capsid (C), precursor membrane (prM), and envelope (E)] and non-structural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) Precursor membrane (prM), one of the ZIKV structural proteins, plays an important role in the assembly of mature virions through cleavage of prM into M protein Recent studies have suggested that prM protein might be implicated in the neurovirulence of ZIKV Most vaccines targeting ZIKV include prM as the immunogen [PMID: 30116235].

Specifications

• Antigen: Zika Virus prM (strain H/PF/2013)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Zika virus Premembrane; Zika virus PrM; ZIKV Premembrane; ZIKV PrM
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Zika virus prM protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.02 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG