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Invitrogen™ Zika Virus prM (strain H/PF/2013) Polyclonal Antibody
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Catalog No. PIPA5143433
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100 μL
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PIPA5143433 100 μL
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Catalog No. PIPA5143433 Supplier Invitrogen™ Supplier No. PA5143433
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Description

Rabbit Polyclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial. Positive control: Zika virus(PRVABC59)-infected Vero, Zika virus prM-infected C6/36.

Zika virus has biological similarities to other flaviviruses, such as West Nile virus, Japanese encephalitis virus (JEV) and dengue virus ZIKV has an approximately 11 kb positive-stranded RNA genome, with untranslated regions flanking the 5' and 3' ends of its open reading frame The genome is translated into structural proteins [capsid (C), precursor membrane (prM), and envelope (E)] and non-structural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) Precursor membrane (prM), one of the ZIKV structural proteins, plays an important role in the assembly of mature virions through cleavage of prM into M protein Recent studies have suggested that prM protein might be implicated in the neurovirulence of ZIKV Most vaccines targeting ZIKV include prM as the immunogen [PMID: 30116235].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Zika Virus prM (strain H/PF/2013)
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% Proclin 300; pH 7
Gene Alias Zika virus Premembrane; Zika virus PrM; ZIKV Premembrane; ZIKV PrM
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Zika virus prM protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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