Invitrogen™ Zika Virus prM (strain H/PF/2013) Polyclonal Antibody

Catalog No.	Quantity
PIPA5143443	100 μL

Catalog No. PIPA5143443 Supplier Invitrogen™ Supplier No. PA5143443

Description

Rabbit Polyclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial. Positive control: Zika virus prM-infected C6/36.

Zika virus has biological similarities to other flaviviruses, such as West Nile virus, Japanese encephalitis virus (JEV) and dengue virus ZIKV has an approximately 11 kb positive-stranded RNA genome, with untranslated regions flanking the 5' and 3' ends of its open reading frame The genome is translated into structural proteins [capsid (C), precursor membrane (prM), and envelope (E)] and non-structural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) Precursor membrane (prM), one of the ZIKV structural proteins, plays an important role in the assembly of mature virions through cleavage of prM into M protein Recent studies have suggested that prM protein might be implicated in the neurovirulence of ZIKV Most vaccines targeting ZIKV include prM as the immunogen [PMID: 30116235].

Specifications

• Antigen: Zika Virus prM (strain H/PF/2013)
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.53 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
• Gene Alias: Zika virus Premembrane; Zika virus PrM; ZIKV Premembrane; ZIKV PrM
• Host Species: Rabbit
• Immunogen: Full length Zika virus prM recombinant protein. (Zika virus (strain H/PF/2013)).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG