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Invitrogen™ ZIP10 Polyclonal Antibody
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Catalog No. PIPA557697
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PIPA557697 100 μL
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Catalog No. PIPA557697 Supplier Invitrogen™ Supplier No. PA557697
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EKETVEVSVK SDDKHMHDHN HRLRHHHRLH HHLDHNNTHH FHNDSITPSE RGEPSNEPST ETNKTQEQSD VKLPKGKRKK KGRKSNENSE VITPGFP Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 65%.

ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZIP10
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC39A10
Gene Accession No. Q9ULF5
Gene Alias 2900042E17Rik; 5430433I10; Kiaa1265; LZT-Hs2; mKIAA1265; Slc39a10; solute carrier family 39 (metal ion transporter), member 10; solute carrier family 39 (zinc transporter), member 10; solute carrier family 39 member 10; Zinc transporter ZIP10; ZIP10; ZIP-10; Zrt- and Irt-like protein 10
Gene Symbols SLC39A10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZIP10. Recombinant protein control fragment (Product #RP-96228).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57181
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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