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Invitrogen™ ZIP12 Polyclonal Antibody
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Catalog No. PIPA590883
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100 μL
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PIPA590883 100 μL
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Catalog No. PIPA590883 Supplier Invitrogen™ Supplier No. PA590883
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MCFRTKLSVS WVPLFLLLSR VFSTETDKPS AQDSRSRGSS GQPADLLQVL SAGDHPPHNH SRSLIKTLLE KTGCPRRRNG MQGDCNLCFE PDALLLIAGG; Positive Samples: 293T, mouse brain, mouse eye, mouse lung, rat brain.

The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZIP12
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.62 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SLC39A12
Gene Accession No. Q504Y0, Q5FWH7
Gene Alias AW046938; bA570F3.1; Gm731; LIV-1 subfamily of ZIP zinc transporter 8; LZT-Hs8; Slc39a12; solute carrier family 39 (metal ion transporter), member 12; solute carrier family 39 (zinc transporter), member 12; solute carrier family 39 member 12; Zinc transporter ZIP12; Zip12; ZIP-12; Zrt- and Irt-like protein 12
Gene Symbols SLC39A12
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221074, 277468, 291328
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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