Invitrogen™ ZIP13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521076

Catalog No. PIPA521076

Description

A suggested positive control is K562 cell lysate. PA5-21076 can be used with blocking peptide PEP-1190.

The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.

Specifications

• Antigen: ZIP13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC39A13
• Gene Alias: LIV-1 subfamily of ZIP zinc transporter 9; LZT-Hs9; SLC39A13; solute carrier family 39 (metal ion transporter), member 13; solute carrier family 39 (zinc transporter), member 13; solute carrier family 39 member 13; Zinc transporter ZIP13; ZIP13; ZIP-13; Zrt- and Irt-like protein 13
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91252
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q96H72
• Gene Symbols: SLC39A13
• Immunogen: A 14 amino acid peptide near the amino terminus of human ZIP13.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG