Invitrogen™ ZIP14 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587880

Catalog No. PIPA587880

Description

Positive Samples: LO2, HeLa; Cellular Location: Cell membrane, Cell projection, Multi-pass membrane protein, lamellipodium Immunogen sequence: EENEQTEEGR PSAVE.

The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

Specifications

• Antigen: ZIP14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC39A14
• Gene Alias: cig19; Factor for adipocyte differentiation 123; Fad123; FAD-123; HMNDYT2; Kiaa0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; SLC39A14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; solute carrier family 39 member 14; Zinc transporter ZIP14; Zip14; ZIP-14; Zrt- and Cig19; Zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 213053, 23516, 306009
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.6 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15043, Q75N73
• Gene Symbols: SLC39A14
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 101-200 of human ZIP14 (NP_0011219031).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov