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Invitrogen™ ZIP4 Polyclonal Antibody
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Catalog No. PIPA5101971
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PIPA5101971 100 μL
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Catalog No. PIPA5101971 Supplier Invitrogen™ Supplier No. PA5101971
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SLC39A4.

The zinc transporter ZIP4, also known as SLC39A4, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP4 was initially identified as zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in the absorption of dietary zinc. Similar to other ZIP family members, aberrant expression of ZIP4 has been linked to cancer, specifically the progression and aggressiveness of pancreatic cancer. ZIP4 expression has also been shown to be activated in hepatocellular carcinomas, acting to repress apoptosis, enhance cell cycle and increase migration, suggesting ZIP4 may play a role in multiple types of cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZIP4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Slc39a4
Gene Accession No. Q6P5W5
Gene Alias 1600025H15Rik; activated in W/Wv mouse stomach 2; AEZ; AU041686; AWMS2; EMBL:AAI27515.1}; mAWMS2; SLC39A4; slc39a4 {ECO:0000312; solute carrier family 39 (zinc transporter), member 4; solute carrier family 39 member 4; Zinc transporter ZIP4; Zip4; ZIP-4; Zrt- and Irt-like protein 4
Gene Symbols Slc39a4
Host Species Rabbit
Immunogen A synthesized peptide derived from human SLC39A4(Accession Q6P5W5), corresponding to amino acid residues D433-N483.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55630
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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