Invitrogen™ ZIPK Monoclonal Antibody (4H4C8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531710

Catalog No. PIMA531710

Description

MA5-31710 has been tested in indirect ELISA.

DAPK3 is a serine/threonine kinase which is functionally linked to cell motility, smooth muscle contractility and cell death processes. DAPK3 is encoded by ZIPK and is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Specifications

• Antigen: ZIPK
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: O43293
• Gene Symbols: DAPK3
• Immunogen: Purified recombinant fragment of human DAPK3 (AA: 28-161) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4H4C8
• Conjugate: Unconjugated
• Gene: DAPK3
• Gene Alias: DAP kinase 3; DAP3K; Dapk3; Dapkl; DAP-like kinase; death associated protein kinase 3; death-associated kinase 3; Death-associated like kinase; death-associated protein kinase 3; DLK; MYPT1 kinase; ZIP; ZIP kinase; ZIP kinase isoform; Zipk; ZIP-kinase; zipper-interacting protein kinase
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 1613
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid