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Invitrogen™ ZIPK Polyclonal Antibody
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Catalog No. PIPA527700
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100 μL
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PIPA527700 100 μL
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Catalog No. PIPA527700 Supplier Invitrogen™ Supplier No. PA527700
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549. Predicted reactivity: Mouse (96%), Rat (96%), Xenopus laevis (87%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DAPK3 is a serine/threonine kinase which is functionally linked to cell motility, smooth muscle contractility and cell death processes. DAPK3 is encoded by ZIPK and is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZIPK
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.61 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene DAPK3
Gene Accession No. O43293, O54784, O88764
Gene Alias DAP kinase 3; DAP3K; Dapk3; Dapkl; DAP-like kinase; death associated protein kinase 3; death-associated kinase 3; Death-associated like kinase; death-associated protein kinase 3; DLK; MYPT1 kinase; ZIP; ZIP kinase; ZIP kinase isoform; Zipk; ZIP-kinase; zipper-interacting protein kinase
Gene Symbols DAPK3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human DAP Kinase 3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13144, 1613, 64391
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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