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  5. Tocris Bioscience™ ZJ 43

Tocris Bioscience™ ZJ 43

Catalog No. 26751R
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Glutamate carboxypeptidase II and III (NAALADase, NAAG peptidase) inhibitor

Potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III/NAAG peptidase/NAALADase) (Ki values are 0.8 and 23nM respectively) that inhibits the hydrolysis of NAAG (IC50 = 2.4nM) . Does not directly interact with NMDA or metabotropic glutamate receptors. Reduces neuronal degeneration in a rat model of? traumatic brain injury (TBI) and reduces locomotor activity in the PCP-model of schizophrenia.

Specifications

Chemical Name or Material N-[[[(1S)-1-Carboxy-3-methylbutyl]amino]carbonyl]-L-glutamic acid
CAS 723331-20-2
Quantity 1 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C12H20N2O7
Formula Weight Observed MW: 304.3

For Research Use Only

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