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Invitrogen™ ZMYM2 Polyclonal Antibody
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Catalog No. PIPA528265
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100 μL
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PIPA528265 100 μL
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Catalog No. PIPA528265 Supplier Invitrogen™ Supplier No. PA528265
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: human ESC. Predicted reactivity: Mouse (95%), Rhesus Monkey (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZMYM2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene ZMYM2
Gene Accession No. Q9CU65, Q9UBW7
Gene Alias 5830413P05Rik; FIM; Fused in myeloproliferative disorders protein; MYM; RAMP; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; SCLL; Zfp198; zinc finger MYM-type containing 2; zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2; Zmym2; ZNF198
Gene Symbols ZMYM2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ZNF198. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 76007, 7750
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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