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Invitrogen™ ZMYM2 Polyclonal Antibody
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Catalog No. PIPA583208
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100 μL
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Catalog No. Quantity
PIPA583208 100 μL
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Catalog No. PIPA583208 Supplier Invitrogen™ Supplier No. PA583208
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RLSFGTVFRH WKKNPLTMEN KACLRYQVSS LCGTDNEDKI TTGKRKHEDD EPVFEQIENT ANPSRCPVKM FECYLSKSPQ N Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 98%.

ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZMYM2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZMYM2
Gene Accession No. Q9UBW7
Gene Alias 5830413P05Rik; FIM; Fused in myeloproliferative disorders protein; MYM; RAMP; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; SCLL; Zfp198; zinc finger MYM-type containing 2; zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2; Zmym2; ZNF198
Gene Symbols ZMYM2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZMYM2. Recombinant protein control fragment (Product #RP-95485).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7750
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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