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ZMYM2/ZNF198 Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS13603R

Catalog No. 50-198-3014



Description

Description

ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.
Specifications

Specifications

ZMYM2/ZNF198
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
ZMYM2
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
7750
ZMYM2
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q9UBW7
5830413P05Rik; FIM; Fused in myeloproliferative disorders protein; MYM; RAMP; rearranged in an atypical myeloproliferative disorder; Rearranged in atypical myeloproliferative disorder protein; RP11-264J4.7; SCLL; Zfp198; zinc finger MYM-type containing 2; Zinc finger MYM-type protein 2; Zinc finger protein 198; zinc finger, MYM-type 2; ZMYM2; ZNF198
KLH conjugated synthetic peptide derived from mouse ZMYM2/ZNF198.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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