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Invitrogen™ ZNF692 Polyclonal Antibody
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Catalog No. PIPA5107322
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100 μL
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PIPA5107322 100 μL
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Catalog No. PIPA5107322 Supplier Invitrogen™ Supplier No. PA5107322
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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%.

ZNF692, a zinc finger protein, is involved in several cellular processes including nucleolar organization and ribosome biogenesis. It interacts with nucleophosmin (NPM1), regulating nucleolar morphology by modifying NPM1's self-assembly properties and influencing protein synthesis. Knockdown of ZNF692 causes nucleolar redistribution of NPM1 and results in a decreased rate of protein synthesis. Additionally, ZNF692 plays a role in 40S ribosomal subunit maturation by forming a hub with the exosome complex and ribosome biogenesis factors. This gene is upregulated in certain cancers such as clear cell renal cell carcinoma (ccRCC), where its expression is associated with increased cell proliferation, migration, and poor overall survival.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF692
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene ZNF692
Gene Accession No. Q9BU19
Gene Alias AICAR responsive element binding protein; AREBP; Zfp692; zinc finger protein 692; ZNF692
Gene Symbols ZNF692
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human ZNF692.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55657
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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