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Invitrogen™ ZNF174 Polyclonal Antibody
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Catalog No. PIPA536201
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100 μL
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PIPA536201 100 μL
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Catalog No. PIPA536201 Supplier Invitrogen™ Supplier No. PA536201
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 46 kDa. Purity is >95% by SDS-PAGE.

ZNF174, also known as ZSCAN8 or AW-1, is a transcriptional repressor that belongs to the Krueppel C2H2-type zinc-finger protein family. It is expressed in a number of different tissues, including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney and thymus, but it is most predominantly found in adult ovary and testis. ZNF174 specifically acts to repress the promoter activities of PDGF-B and TGF beta1. ZNF174 localizes to the nucleus and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. SCAN domains are found in a number of zinc-finger proteins and are characterized by a conserved region of 84 residues. The SCAN domain seemingly regulates the association of proteins containing SCAN domains into noncovalent complexes and may also function as an underlying mechanism in selective oligomerization of these proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF174
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ZNF174
Gene Accession No. Q15697
Gene Alias AW1; AW-1; zinc finger and SCAN domain-containing protein 8; Zinc finger protein 174; ZNF174; ZSCAN8
Gene Symbols ZNF174
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 168-228 of human ZNF174.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7727
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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