Invitrogen™ ZNF174 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599286

Catalog No. PIPA599286

Description

Antibody detects endogenous levels of total ZNF174.

ZNF174, also known as ZSCAN8 or AW-1, is a transcriptional repressor that belongs to the Krueppel C2H2-type zinc-finger protein family. It is expressed in a number of different tissues, including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney and thymus, but it is most predominantly found in adult ovary and testis. ZNF174 specifically acts to repress the promoter activities of PDGF-B and TGF beta1. ZNF174 localizes to the nucleus and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. SCAN domains are found in a number of zinc-finger proteins and are characterized by a conserved region of 84 residues. The SCAN domain seemingly regulates the association of proteins containing SCAN domains into noncovalent complexes and may also function as an underlying mechanism in selective oligomerization of these proteins.

Specifications

• Antigen: ZNF174
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZNF174
• Gene Alias: AW1; AW-1; zinc finger and SCAN domain-containing protein 8; Zinc finger protein 174; ZNF174; ZSCAN8
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7727
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q15697
• Gene Symbols: ZNF174
• Immunogen: A synthesized peptide derived from human ZNF174(Accession Q15697), corresponding to amino acid residues P189-S239.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG