ZNF268 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0400	100 μL

Catalog No. 50-198-0400 Supplier Bioss Supplier No. BS0626R

Description

Rabbit Polyclonal Antibody

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events.

Specifications

• Antigen: ZNF268
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ZNF268
• Gene Accession No.: Q14587
• Gene Alias: HZF3; Zinc finger protein 268; zinc finger protein 3; Zinc finger protein HZF3; ZNF268
• Gene Symbols: ZNF268
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human ZNF268.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10795
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG