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Invitrogen™ ZNF281 Polyclonal Antibody
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Catalog No. PIPA528290
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100 μL
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PIPA528290 100 μL
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Catalog No. PIPA528290 Supplier Invitrogen™ Supplier No. PA528290
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: ZNF281 tansfected 293T cell. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF281
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene ZNF281
Gene Accession No. Q9Y2X9
Gene Alias GC-box-binding zinc finger protein 1; GZP1; Transcription factor ZBP-99; ZBP99; ZBP-99; Zfp281; Zinc finger DNA-binding protein 99; zinc finger protein 281; ZNF281; ZNP-99; ZNP-99 transcription factor
Gene Symbols ZNF281
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ZNF281. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23528
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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