Invitrogen™ ZNF306 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552671

Catalog No. PIPA552671

Description

Immunogen sequence: LLTPAPGSQS SQFQLMKALL KHESVGSQPL QDRVLQVPVL AHGGCCREDK VVASRLTPES QGLLKVEDVA LTLTPEWTQQ DSSQGNLCRD EKQENHGSLV SLGDEKQTKS RDLPPAEELP EKEHGKISCH LREDIAQIPT CAEAGEQEGR Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 59%.

ZNF306 is a protein coding gene. Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.

Specifications

• Antigen: ZNF306
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZKSCAN3
• Gene Alias: 2810435N07Rik; AA408594; AI132359; dJ874C20.1; dJ874C20.1.; mszf35; SCAN-KRAB-zinc finger gene 1; SCAN-KRAB-zinc finger protein; Skz1; Zf47; ZFP306; Zfp307; Zfp47; zfp-47; Zinc finger and SCAN domain-containing protein 13; zinc finger protein 306; Zinc finger protein 307; zinc finger protein 309; Zinc finger protein 47 homolog; zinc finger protein with KRAB and SCAN domains 3; zinc finger protein zfp47; zinc finger with KRAB and SCAN domains 3; Zkscan3; ZNF306; ZNF309; ZSCAN13; ZSCAN35
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80317
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BRR0
• Gene Symbols: ZKSCAN3
• Immunogen: Recombinant protein corresponding to Human ZNF306. Recombinant protein control fragment (Product #RP-89451).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG