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Invitrogen™ ZNF408 Polyclonal Antibody
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Catalog No. PIPA553660
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PIPA553660 100 μL
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Catalog No. PIPA553660 Supplier Invitrogen™ Supplier No. PA553660
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AAVAVVTEVE SAVQQEVASP GEDAAEPCID PGSQSPSGIQ AENMVSPGLK FPTQDRISKD SQPLGPLLQD GDVDEECPAQ AQMPPELQSN SATQQDPDGS GASFSSSARG TQPHGYLAKK LHSPSDQCPP RAKTPEPGAQ QSGFPTLSRS Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 25%.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kruppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains 10 C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF408
Applications ChIP Assay, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZNF408
Gene Accession No. Q9H9D4
Gene Alias EVR6; LOC100362202; PFM14; PR domain zinc finger protein 17; PRDM17; RP72; Zinc finger protein 408; ZNF408
Gene Symbols ZNF408
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZNF408. Recombinant protein control fragment (Product #RP-91666).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79797
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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