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Invitrogen™ ZNF423 Polyclonal Antibody
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Catalog No. PIPA5107321
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100 μL
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PIPA5107321 100 μL
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Catalog No. PIPA5107321 Supplier Invitrogen™ Supplier No. PA5107321
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Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.

Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF423
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene ZNF423
Gene Accession No. Q2M1K9
Gene Alias early B-cell factor associated zinc finger protein; Ebfaz; hOAZ; JBTS19; KIAA0760; NPHP14; OAZ; OLF-1/EBF associated zinc finger; olf1/EBF-associated zinc finger protein; Roaz; Smad- and Olf-interacting zinc finger protein; Zfp104; ZFP423; zinc finger protein 423; ZNF423
Gene Symbols ZNF423
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human ZNF423 (aa 1234-1284).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23090
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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