Invitrogen™ ZNF423 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566798

Catalog No. PIPA566798

Description

Immunogen sequence: QPDSSNHSVSP DPVLGSVASM SSATPDSSAS VERGSTPDST LKPLRGQKKM RDDGQGWTKV Highest antigen sequence identity to the following orthologs - mouse 97%, rat 97%.

Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Specifications

• Antigen: ZNF423
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZNF423
• Gene Alias: early B-cell factor associated zinc finger protein; Ebfaz; hOAZ; JBTS19; KIAA0760; NPHP14; OAZ; OLF-1/EBF associated zinc finger; olf1/EBF-associated zinc finger protein; Roaz; Smad- and Olf-interacting zinc finger protein; Zfp104; ZFP423; zinc finger protein 423; ZNF423
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23090
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2M1K9
• Gene Symbols: ZNF423
• Immunogen: Recombinant Human ZNF423. Recombinant protein control fragment (Product #RP-107457).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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