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Invitrogen™ ZNF451 Polyclonal Antibody
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Catalog No. PIPA569000
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100 μL
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Catalog No. Quantity
PIPA569000 100 μL
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Catalog No. PIPA569000 Supplier Invitrogen™ Supplier No. PA569000
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 87%; Rat: 100%.

E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation. Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF451
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene ZNF451
Gene Accession No. Q9Y4E5
Gene Alias 4930515K21Rik; 4933435G09Rik; AI596398; Coactivator for steroid receptors; COASTER; dJ417I1.1; E3 SUMO-protein ligase ZNF451; E3 SUMO-protein ligase ZNF451; zinc finger protein 451; E3 SUMO-protein transferase ZNF451; KIAA0576; Kiaa0576-hp; KIAA1702; mKIAA1702; Zfp451; Zinc finger protein 451; Zinc finger protein 451-like protein; Znf451
Gene Symbols ZNF451
Host Species Rabbit
Immunogen synthetic peptide directed towards the C terminal region of human ZNF451.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26036
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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